Consult a health care practitioner if symptoms persist or worsen prior to use if you have stomach ulcers or inflammation, if you are taking immunosuppressants, or if you have a progressive systemic disease such as tuberculosis, leukosis, collagenosis or multiple sclerosis, if you have a kidney disorder or if you have blood pressure problems. Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family or if you are pregnant or breastfeeding. Hypersensitivity (e.g. allergy) has been known to occur, in which case, discontinue use. Consumption of Golden Seal with alcohol, other medications and/or natural health products with sedative properties is not recommended.