Use only as directed by a health care practitioner. Consult a health care practitioner prior to use if you are taking hormone-containing medications such as progesterone preparations, oral contraceptives or hormonal replacement therapy. Consult a health care practitioner if pain or symptoms persist. Chaste Tree may interact antagonistically with dopamine receptor antagonists. Chaste Tree is best not taken in conjunction with progesterone drugs, contraceptive pill or hormone replacement therapy (HRT). Chaste Tree may aggravate pure spasmodic dysmenorrhoea not associated with premenstrual syndrome (PMS). Use cautiously in pregnancy and only in the early stages for treatment of insufficient corpus luteal function. Discontinue use 7 days prior to general anaesthesia.